The Surprising Connection Between Cancer and Allergy
IgE, best known for mediating allergic reactions, may also shape cancer outcomes.
Learn how this immune molecule could serve as both a biomarker and a basis for next-generation therapies.
IgE, a key indicator of allergic diseases, is increasingly recognized for its potential role in tumor immunity.
Immunoglobulin E (IgE) is evolutionarily thought to play a role in immune responses against parasitic infections, but its pathophysiology is associated with the development of allergies.
Detecting serum IgE specific to an allergen is the primary determinant of allergy.
IgE produced by plasma cells binds to its canonical receptor FCεR1 on mast cells and basophils, priming them for antigen re-exposure.
No specific quote available in the text.
Author's summary: IgE links allergy and cancer.
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