ONL Therapeutics randomizes first patient in phase 2 GALAXY trial evaluating xelafaslatide | Ophthalmology Times - Clinical Insights for Eye Specialists

ONL Therapeutics Initiates Phase 2 GALAXY Trial for Xelafaslatide

ONL Therapeutics has randomized the first patient in its phase 2 GALAXY trial, evaluating xelafaslatide for geographic atrophy associated with dry age-related macular degeneration.

Xelafaslatide, formerly known as ONL1204, is a small-molecule Fas inhibitor designed to protect key retinal cells from cell death.

Xelafaslatide is a small-molecule Fas inhibitor designed to protect key retinal cells, including photoreceptors, from cell death that occurs across multiple retinal diseases and conditions.

The company announced that xelafaslatide is the newly established nonproprietary name for ONL1204 Ophthalmic Solution, following approval from the World Health Organization and the United States Adopted Names Council.

Author's summary: ONL Therapeutics starts phase 2 trial for xelafaslatide.

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Ophthalmology Times Ophthalmology Times — 2025-10-28

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